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Title: Sample size calculation : influence of confounding and interaction effects
Authors: Tse, Kwok Ho
Issue Date: 2006
Abstract: In this thesis, we first introduce four different approaches in case-control studies with the association of confounding and interaction effect and then compare their sample sizes based on normal approximation for a specified power at a certain significance level. These approaches are: (1) an unmatched design with an unstratified analysis; (2) an unmatched design with a stratified analysis; (3) a matched design with an unstratified analysis; (4) a matched design with a stratified analysis. We also develop the analysis for case-control studies with two exposure variables using maximum likelihood method. Calculation of sample size required to detect the interaction effect between two exposure variables in the presence of a confounding variable.
Description: Thesis (M.Phil.)--Hong Kong University of Science and Technology, 2006
xvii, 102 leaves : ill. ; 30 cm
HKUST Call Number: Thesis MATH 2006 Tse
Appears in Collections:MATH Master Theses

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