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Title: Design and integration of an all-in-one biomicrofluidic chip
Authors: Liu, Liyu
Cao, Wenbin
Wu, Jinbo
Wen, Wei-Jia
Chang, Donald C.
Sheng, Ping
Keywords: Biomicrofluidic chip
DNA amplification
GER fluid-actuated micromixer
Microheater array
Soft lithography
Issue Date: 21-Jul-2008
Citation: Biomicrofluidics, v. 2, iss. 3, p. 034103, 2008
Abstract: We demonstrate a highly integrated microfluidic chip with the function of DNA amplification. The integrated chip combines giant electrorheological-fluid actuated micromixer and micropump with a microheater array, all formed using soft lithography. Internal functional components are based on polydimethylsiloxane (PDMS) and silver/carbon black-PDMS composites. The system has the advantages of small size with a high degree of integration, high polymerase chain reaction efficiency, digital control and simple fabrication at low cost. This integration approach shows promise for a broad range of applications in chemical synthesis and biological sensing/analysis, as different components can be combined to target desired functionalities, with flexible designs of different microchips easily realizable through soft lithography. © 2008 American Institute of Physics.
Rights: Biomicrofluidics © copyright 2008 American Institute of Physics. The journal's web site is located at
Appears in Collections:BIOL Journal/Magazine Articles
PHYS Journal/Magazine Articles

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