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http://hdl.handle.net/1783.1/6769
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| Title: | A point-of-care immunotest for bedside determination of heart-type fatty acid-binding protein |
| Authors: | Tong, Chao-Yang
Chan, Cangel Pui Yee
Cheung, Kwan-yee
Cautherley, George W. H.
Glatz, Jan F. C.
Renneberg, Reinhard |
| Keywords: | Acute myocardial infarction
Bedside
Cardiac troponin T
Creatine kinase MB
Heart-type fatty acid-binding protein
Myoglobin
Point-of-care |
| Issue Date: | Mar-2010 |
| Citation: | Analytical letters, v. 43, iss. 4, p. 735-744 |
| Abstract: | Ninety-one patients presenting to the Emergency Department suspected of acute myocardial infarction (AMI) with a median symptom onset of 6 h, of which 75 had AMI. A point-of-care immunotest for heart-type fatty acid-binding protein (H-FABP) was found to have a significant better sensitivity than the other markers and a better specificity than myoglobin and creatinine kinase MB. H-FABP gave the greatest area under the receiver operating characteristic curve (0.864) for those admitted within 6 h. H-FABP was also found to be the most efficient marker to diagnose patients suspected of AMI without ST-elevation and with a negative cardiac troponin T. |
| Rights: | This is a preprint of an article whose final and definitive form has been published in the Analytical Letters c 2010 copyright Taylor & Francis; Analytical Letters is available online at: http://www.informaworld.com |
| URI: | http://hdl.handle.net/1783.1/6769 |
| Appears in Collections: | CHEM Journal/Magazine Articles
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Size | Format |
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| OriginalArticle_RennebergR_AnalLett2010.pdf | pre-published version | 202Kb | Adobe PDF | View/Open |
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