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|Title: ||A point-of-care immunotest for bedside determination of heart-type fatty acid-binding protein|
|Authors: ||Tong, Chao-Yang|
Chan, Cangel Pui Yee
Cautherley, George W. H.
Glatz, Jan F. C.
|Keywords: ||Acute myocardial infarction|
Cardiac troponin T
Creatine kinase MB
Heart-type fatty acid-binding protein
|Issue Date: ||Mar-2010 |
|Citation: ||Analytical letters, v. 43, iss. 4, p. 735-744|
|Abstract: ||Ninety-one patients presenting to the Emergency Department suspected of acute myocardial infarction (AMI) with a median symptom onset of 6 h, of which 75 had AMI. A point-of-care immunotest for heart-type fatty acid-binding protein (H-FABP) was found to have a significant better sensitivity than the other markers and a better specificity than myoglobin and creatinine kinase MB. H-FABP gave the greatest area under the receiver operating characteristic curve (0.864) for those admitted within 6 h. H-FABP was also found to be the most efficient marker to diagnose patients suspected of AMI without ST-elevation and with a negative cardiac troponin T.|
|Rights: ||This is a preprint of an article whose final and definitive form has been published in the Analytical Letters c 2010 copyright Taylor & Francis; Analytical Letters is available online at: http://www.informaworld.com|
|Appears in Collections:||CHEM Journal/Magazine Articles|
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