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Hybrid Approach to High-Frequency Microfluidic Mixing

Authors Niu, Xize HKUST affiliated (currently or previously)
Liu, Liyu HKUST affiliated (currently or previously)
Wen, Weijia View this author's profile
Sheng, Ping View this author's profile
Issue Date 2006
Source Physical Review Letters , v. 97, (4), July 2006, Article number 044501
Summary We report the experimental verification of the predicted chaotic mixing characteristics for a polydimethylsioxane microfluidic chip, based on the mechanism of multistage cross-channel flows. While chaotic mixing can be achieved within short passage distances, there is an optimal side channel flow pulsation frequency beyond which the mixing becomes ineffective. Based on the physical understanding of a Poincare section analysis, we propose the installation of passive flow baffles in the main microfluidic channel to facilitate high-frequency mixing. The combined hybrid approach enables chaotic mixing at enhanced frequency and reduced passage distance in two-dimensional flows.
ISSN 0031-9007
Rights © 2006 The American Physical Society
Language English
Format Article
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