Please use this identifier to cite or link to this item: http://hdl.handle.net/1783.1/3368

抗寄生虫青蒿素衍生物,制备方法及组合物和用途

Antiparasitic artemisinin derivatives, its preparing method and composition and use

Antiparasitic artemisinin derivatives (endoperoxides)

Authors R·K·郗能治
陈浩怀
林威伦
曾庆和
张文骥
A·沃尔斯特
G·施穆克
G·格雷夫
Issue Date 2003-09-24
Source 中国专利 , ZL 99 8 10650.X, 2003
Summary 本发明涉及某些通式(I)的C-10取代的青蒿素衍生物治疗和/或预防由寄生虫感染所引起的疾病的用途、某些新的C-10取代的青蒿素衍生物、其制备方法以及含有这些C-10取代的衍生物的药用组合物。这些化合物在治疗疟疾、新孢子虫病和球虫病中特别有效。This invention relates to the use of certain C-10 substituted derivatives of artemisinin of general formula (I) in the treatment and/or prophylaxis of diseases caused by infection with a parasite, certain novel C-10 substitued derivatives of artemisinin, processes for their preparation and pharmaceutical compositions containing such C-10 substituted derivatives. The compounds are particularly effective in the treatment of malaria, neosporosis and coccidiosis.
Subjects
Language Chinese
Format Patent
Access View details of TTC.PA.072 via HKUST Technology Transfer Center