Please use this identifier to cite or link to this item: http://hdl.handle.net/1783.1/3556

Ca<sup>2+</sup> signaling during embryonic cytokinesis in animal systems

Authors Webb, S.E.
Miller, A.L.
Issue Date 2007
Source New Comprehensive Biochemistry , / Edited by Joachim Krebs, Marek Michalak. Amsterdam : Elsevier, 2007, p. 445-470
Summary In this chapter, we provide a review of the literature that describes the role of Ca<sup>2+</sup> signaling during embryonic cytokinesis in animal systems. We begin with a historic overview (starting with the earliest reports published in the latter part of the nineteenth century) that gives some of the first descriptions linking Ca<sup>2+</sup> with cell division in embryos. This introductory overview also outlines the different techniques that were used and developed over time, from the pre-Ca<sup>2+</sup> imaging days through to the sophisticated approaches that are available today for directly visualizing Ca<sup>2+</sup> signals in living cells. In the remainder of the chapter, we describe the more recent advances in cytokinetic Ca<sup>2+</sup>-signaling research, starting where the introduction finished, in the 1990s. Reports of the various Ca<sup>2+</sup> signals visualized during cytokinesis in fish, amphibian, echinoderm, and insect embryos using both fluorescent and luminescent Ca<sup>2+</sup> probes are described, as well as the investigations carried out to determine both the requirement of elevated Ca<sup>2+</sup> during cytokinesis and the source of the Ca<sup>2+</sup> involved in this process. The current hypotheses regarding the possible roles and targets of the different cytokinetic Ca<sup>2+</sup> signals observed are also briefly discussed. © 2007 Elsevier B.V. All rights reserved.
Subjects
ISSN 0167-7306
ISBN 0444528059
9780444528056
Rights 'New comprehensive biochemistry © copyright 2007 Elsevier. The Journal's web site is located at http://www.sciencedirect.com/
Language English
Format Book chapter
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