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Design and Integration of an All-in-one Biomicrofluidic Chip

Authors Liu, Liyu HKUST affiliated (currently or previously)
Cao, Wenbin HKUST affiliated (currently or previously)
Wu, Jinbo HKUST affiliated (currently or previously)
Wen, Weijia View this author's profile
Chang, Donald C HKUST affiliated (currently or previously)
Sheng, Ping View this author's profile
Issue Date 2008
Source Biomicrofluidics , v. 2, (3), September 2008, article number 034103
Summary We demonstrate a highly integrated microfluidic chip with the function of DNA amplification. The integrated chip combines giant electrorheological-fluid actuated micromixer and micropump with a microheater array, all formed using soft lithography. Internal functional components are based on polydimethylsiloxane (PDMS) and silver/carbon black-PDMS composites. The system has the advantages of small size with a high degree of integration, high polymerase chain reaction efficiency, digital control and simple fabrication at low cost. This integration approach shows promise for a broad range of applications in chemical synthesis and biological sensing/analysis, as different components can be combined to target desired functionalities, with flexible designs of different microchips easily realizable through soft lithography. (c) 2008 American Institute of Physics.
ISSN 1932-1058
Rights Biomicrofluidics © copyright 2008 American Institute of Physics. The journal's web site is located at
Language English
Format Article
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