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Design and Integration of an All-in-one Biomicrofluidic Chip

Authors Liu, Liyu
Cao, Wenbin
Wu, Jingbo
Wen, Weijia
Chang, Donald Choy
Sheng, Ping
Issue Date 2008
Source Biomicrofluidics , v. 2, (3), 2008, Sep, article number 034103
Summary We demonstrate a highly integrated microfluidic chip with the function of DNA amplification. The integrated chip combines giant electrorheological-fluid actuated micromixer and micropump with a microheater array, all formed using soft lithography. Internal functional components are based on polydimethylsiloxane (PDMS) and silver/carbon black-PDMS composites. The system has the advantages of small size with a high degree of integration, high polymerase chain reaction efficiency, digital control and simple fabrication at low cost. This integration approach shows promise for a broad range of applications in chemical synthesis and biological sensing/analysis, as different components can be combined to target desired functionalities, with flexible designs of different microchips easily realizable through soft lithography. (c) 2008 American Institute of Physics.
ISSN 1932-1058
Rights Biomicrofluidics © copyright 2008 American Institute of Physics. The journal's web site is located at
Language English
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