Please use this identifier to cite or link to this item: http://hdl.handle.net/1783.1/651

Preliminary study of detecting neoplastic growths in vivo with real time calibrated autofluorescence imaging

Authors Wu, T
Qu, JNY
Cheung, TH
Lo, KWK
Yu, MY
Issue Date 2003
Source Optics express, v. 11, (4), 2003, FEB 24, p. 291-298
Summary The goal of this study was to evaluate the capabilities of a calibrated autofluorescence imaging method for detecting neoplastic lesions. An imaging system that records autofluorescence images calibrated by the cross-polarized reflection images from excitation was instrumented for the evaluation. Cervical tissue was selected as the living tissue model. Sixteen human subjects were examined in vivo with the imaging system before routine examination procedures. It was found that calibrated autofluorescence signals from neoplastic lesions were generally lower than signals from normal cervical tissue. Neoplastic lesions can be differentiated from surrounding normal tissue based on the contrast in the calibrated autofluorescence. The effects of the optical properties of tissue on the calibrated fluorescence imaging were investigated. (C) 2003 Optical Society of America.
Subjects
ISSN 1094-4087
Rights We would like to give credit to the Optical Society of America for granting us permission to repost this Optics Express article. The original article is posted on the journal's web site at http://www.opticsexpress.org/abstract.cfm?URI=OPEX-11-4-291
Language English
Format Article
Access View full-text via Web of Science
View full-text via Scopus
Find@HKUST
Files in this item:
File Description Size Format
2026_3969_20441.PDF 1257694 B Adobe PDF
2026_3739.MPG 1610864 B MPEG